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Subject: "Half of men may have HPV infections: study"     Previous Topic | Next Topic
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Conferences HPV (Human Papilloma Virus) Topic #971
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zinnia
Member since Aug-17-08
1012 posts
Mar-01-11, 09:12 AM (CST)
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"Half of men may have HPV infections: study"
 
Half of men may have HPV infections: study
By Julie Steenhuysen

http://www.reuters.com/article/2011/03/01/us-cancer-vaccine-idUSTRE7200CJ20110301

CHICAGO | Mon Feb 28, 2011 7:55pm EST

(Reuters) - Half of men in the general population may be infected with human papillomavirus or HPV, the human wart virus that causes cervical and other cancers, strengthening the case for vaccinating boys against HPV, U.S. researchers said on Monday.

U.S. vaccine advisers have been weighing whether boys and young men should be vaccinated against the human papillomavirus, as they already recommend for girls and young women, but some worry the vaccine is too costly to justify its use.

HPV infection is best known as the primary cause of cervical cancer, the second most common cancer in women worldwide. But various strains of HPV also cause anal, penile, head and neck cancers. Vaccinating men and boys would prevent some of these cancers.

Anna Giuliano of the H Lee Moffitt Cancer Center and Research Institute in Tampa, Florida, and colleagues studied infection rates among more than 1,100 men aged 18 to 70 in the United States, Brazil and Mexico to get a snapshot of the natural progression of HPV infection in men.

"We found that there is a high proportion of men who have genital HPV infections. At enrollment, it was 50 percent," said Giuliano, whose study appears online in the journal Lancet.

The team also found that the rate at which men acquire new HPV infections is very similar to women.

And they found that about 6 percent of men per year will get a new HPV 16 infection, the strain that is known for causing cervical cancer in women and other cancers in men.

Vaccines made by Merck & Co and GlaxoSmithKline both offer protection against this strain of HPV.

"The biology seems to be very similar (to women)," Giuliano said in a telephone interview.

"What is different is men seem to have high prevalence of genital HPV infections throughout their lifespans."

She said it appears that women are better able to clear an HPV infection, especially as they age, but men do not appear to have this same ability.

Vaccine experts said the study builds momentum for widespread HPV vaccination among boys.

Currently, U.S. Centers for Disease Control and Prevention recommends Gardasil vaccinations for girls and women between the ages of 11 and 26. Gardasil had sales of more than $1 billion last year.

And while doctors are free to use the vaccine in boys and men ages 9 through 26, U.S. health officials so far have declined to recommend routine vaccination for males.

"This study highlights the high incidence of HPV infection in men, which emphasizes their role in transmission of HPV to women," Dr. Anne Szarewski of the Wolfson Institute of Preventive Medicine in London said in a statement.

"It must surely strengthen the argument for vaccination of men, both for their own protection, and that of their partners."

In December, the U.S. Food and Drug Administration approved Merck's Gardasil HPV vaccine for prevention of anal cancers in both men and women, based on studies showing Gardasil was effective in men who have sex with men, a group that has a higher incidence of anal cancer.

Anal cancer is one of the less common types of cancer, with an estimated 5,300 new U.S. cases diagnosed each year, but the incidence is increasing.


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zinnia
Member since Aug-17-08
1012 posts
Mar-01-11, 09:15 AM (CST)
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1. "RE: Half of men may have HPV infections: study"
In response to message #0
 
As always, it would be interesting to find out who funded this study. I did find the tidbit about women being able to clear the infection, but men not being as able pretty interesting. For once, women seem to have the (slight) advantage when it comes to STIs.

I just hope we are able to improve testing (a pap smear or something similar) for anal, oral, throat, etc. cancers that are caused by this same virus. An effective blood test would be even more convenient...we can dream, right


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Rajahadmin
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15328 posts
Mar-01-11, 01:56 PM (CST)
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2. "Very Interesting. How did they test for it??"
In response to message #0
 
Am I hopelessly out of date? I didn't think there was a good diagnostic test for HPV in men.

"Do the Right Thing. It will gratify some people and astound the rest." - Paraphrased from Mark Twain


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graceadmin
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13334 posts
Mar-01-11, 05:42 PM (CST)
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3. "RE: Very Interesting. How did they test for it??"
In response to message #2
 
the technicality is - there aren't commercially available hpv tests for males raj. We have plenty of them but they aren't marketed widely. the pap test that is done on women can be used for anuses on both males and female. We also have urine tests for hpv and blood tests however it's my understanding that they are not type specific so no way to know if it's a hpv infection in your mouth, bum, genitals or your foot hence no commercial availability at this time - need carefully controlled conditions such as research studies.

they also have what they call emery paper they use on males. think sand paper for the delicate genital area that they rub over the skin, collect skin cells from and then test for hpv ( much like a pap test ). they don't mention if it's painful or not in the research but I'm sure like many things, the amount of discomfort directly correlates to the person doing it

grace

The first step in stopping the perceived stigma about genital herpes - is to stop believing in it yourself


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graceadmin
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13334 posts
Mar-01-11, 05:47 PM (CST)
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4. "RE: Very Interesting. How did they test for it??"
In response to message #3
 
I hope the vaccine recommendation boards do add it to the list of recommended vaccines for folks. Currently, even though it's approved for males and females, most insurances aren't covering gardasil for males, only females. I think you can get it on most college campuses and at the health department though if you are a male. Not sure of the cost - I know it's between $350-$400 without insurance coverage in general, that's without the added costs the clinic tacks on for giving it to you. I think at this point they are planning on saving money by not covering them because most folks still think of anal cancer in males as a "gay" disease and not something that straight menfolk get too. Hard to sell a std vaccine, easier to sell a cancer preventative vaccine though even at that I think it's like only 1 out of 3 eligible females have had their gardasil shots

grace

The first step in stopping the perceived stigma about genital herpes - is to stop believing in it yourself


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withbaggage
Member since Jun-18-10
18 posts
Mar-02-11, 03:54 PM (CST)
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5. "RE: Half of men may have HPV infections: study"
In response to message #0
 
   I do not know much about HPV really. A person whom i not friends with but know has cervical cancer which she told me was caused by HPV. That was a shocker. I always thought cervical cancer was just that not caused by a std.
anyway i got curious and wejnt to american cancer society web page
it stated that anyone who has edver had sex has come in contactg and got the hpv that most people body clears HPv up and get rid of it
and that when there a case where the body fails to rid itself of HPV
then in males it gives warts and wemon civerical cancer.
if that true then if a man had sex with a woman with cirvical cancer can he catch the HPV Virus from herf?

linda


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