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Subject: "Any thoughts on this paper from the HHP experts?"     Previous Topic | Next Topic
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Staying Upbeat
Member since Jul-31-12
4 posts
Jul-31-12, 05:11 PM (CST)
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"Any thoughts on this paper from the HHP experts?"
 
   There has been some buzz on the other sites about a preliminary study done in France using the VZV vaccine as a therapeutic measure for HSV:
<http://www.dovepress.com/efficacy-of-the-anti-vzv-anti-hsv3-vaccine-in-hsv1-and-hsv2-recurrent--peer-reviewed-article-OAJCT>

The group has even filed a patent:
"USE OF A VACCINE AGAINST THE VZV/HSV3 VIRUS FOR TREATING HSV1 AND/OR HSV2 HERPES VIRUS INFECTIONS" (FRENCH INVENTOR)
Document Type and Number: WIPO Patent Application WO/2011/064254
Kind Code: A1
<http://www.highbeam.com/doc/1P3-2365940721.html>

It seems to have a few technical errors someone with knowledge of Herpes viruses wouldn't make and the placebo effect seems possible but the primary investigator is a legitimate doctor.

Any thoughts?


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  Subject     Author     Message Date     ID  
  RE: Any thoughts on this paper from the HHP experts? windyadmin Aug-02-12 1
     Our patent system is seriously broken... Rajahadmin Aug-04-12 2
  RE: Any thoughts on this paper from the HHP experts? Linda555 Dec-26-12 3
     I have to disagree.. There is presently no cure for herpes. Rajahadmin Dec-30-12 4
  RE: Any thoughts on this paper from the HHP experts? eagledave Jan-22-13 5
     RE: Any thoughts on this paper from the HHP experts? eagledave Jan-29-13 6
         I can check with some of the more academic folks.. Rajahadmin Jan-30-13 8
             I did check with one of the more academic folks.. Rajahadmin Jan-31-13 9
                 RE: I did check with one of the more academic folks.. eagledave Mar-10-13 10
                     I am over 60 and got the shingles vaccine last year.. Rajahadmin Mar-11-13 11
                         RE: How Many People Taking Acyclovir Got Shingles? deb54 Mar-12-13 12
                             RE: How Many People Taking Acyclovir Got Shingles? eagledave Mar-28-13 13
                                 RE: How Many People Taking Acyclovir Got Shingles? deb54 Mar-29-13 14
                                 EagleDave, the herpes antivirals are very safe.. Rajahadmin Mar-29-13 15
                                     RE: EagleDave, the herpes antivirals are very safe.. eagledave Mar-30-13 16
                                         shingles vaccine didnt work for me eagledave May-16-13 17
                                             RE: shingles vaccine didnt work for me Raven00144 May-16-13 18
                                             RE: shingles vaccine didnt work for me Atifrazaa Dec-27-14 20
                                             RE: shingles vaccine didnt work for me eagledave Nov-20-13 19

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windyadmin
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8256 posts
Aug-02-12, 06:54 PM (CST)
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1. "RE: Any thoughts on this paper from the HHP experts?"
In response to message #0
 
I thought this was tried long ago (decades ago) and didn't work, but I couldn't find anything about it on medline. Maybe I need to search longer. And even if I'm right, it's possible that a different VZV vaccine was tested in the past, and it's possible that this one does work.

The lack of a placebo group is really not a problem. This was a pilot study, and they plan to do a controlled study. Those results will be the really interesting ones. The use of two different vaccines with such a small group might be a problem. (note: I don't know if they're really different vaccines manufactured by two different companies, or if one makes it and they both market it.)

I think they mean HHV-3, not HSV-3. VZV is not Herpes simplex, it's Herpes zoster. Maybe it's different in France.

What I find really offensive is that they filed for a patent for this, and I'm disappointed that they got it. It's not a new idea, and they didn't invent anything. Worse, it goes against the whole idea of sharing scientific information. Will they expect to get paid every time some doctor and patient decide to try this?


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Rajahadmin
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Aug-04-12, 04:58 PM (CST)
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2. "Our patent system is seriously broken..."
In response to message #1
 
Patents are issued today for "inventions" that clearly have prior art years or even decades before the application. The other problem is that lots of them are "obvious to anyone skilled in the art". The patent office makes money from the applications so they tend to let things slide to get the revenue.

"Do the Right Thing. It will gratify some people and astound the rest." - Paraphrased from Mark Twain


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Linda555
Member since Dec-26-12
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Dec-26-12, 08:24 AM (CST)
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3. "RE: Any thoughts on this paper from the HHP experts?"
In response to message #0
 
   LAST EDITED ON Dec-30-12 AT 05:04 PM (CST) by Rajah (admin)
 
Maybe the experts on this forum would comment on the research that has been done in universities and laboratories all over the world on plant medicine. The best collection of this research I've found is at *advertising link removed*

It seems to me the only reason people continue to use drugs for herpes is because the drug pushers are making a profit at it and keep their research secret. Researchers have known for years about the plant medicine that will kill the herpes virus but don't want the general public to find out about it.


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Rajahadmin
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Dec-30-12, 05:06 PM (CST)
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4. "I have to disagree.. There is presently no cure for herpes."
In response to message #3
 
See http://nocureforherpes.com/ for an explanation.

"Do the Right Thing. It will gratify some people and astound the rest." - Paraphrased from Mark Twain


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eagledave
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Jan-22-13, 08:49 AM (CST)
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5. "RE: Any thoughts on this paper from the HHP experts?"
In response to message #0
 
LAST EDITED ON Jan-22-13 AT 08:51 AM (CST)
 
The pdf download of the complete publication (at the bottom of that dovetail site) was pretty stunning, if accurate. And there was a control group, but I dont believe it was a blind experiment.
Perhaps we dont hear more anecdotal stories from those vaccinated having a cessation of OBs because the vaccinated are typically older and either dont make the connection or have less OBs in general.

I read on herpes site "H Harmony" that some people are giving the vaccine a try, as it does not require a prescription and can even be got at Walgreens. My main question is whether it's the same vaccine? It's also abit pricey.
http://www.hsvsinglesdating.com/articles/view/20/A-potential-Herpes-vaccine/index.html

H Harmony also listed a herpes vaccine in the works from Genocea Biosciences:
http://www.hsvsinglesdating.com/articles/view/22/Herpes-Cure-Research,-Potential-Vaccines,-Genocea-Biosciences/index.html


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eagledave
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Jan-29-13, 07:06 PM (CST)
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6. "RE: Any thoughts on this paper from the HHP experts?"
In response to message #5
 
downside is there's an age minimum to get the Shingles vaccine. The FDA ruled it's okay for 50+ yo.
They highly recommend it for 60+. Unfortunately this recommended age is misinterpreted as the minimum age limit by most pharmacies and doctors. But even if docs are willing to vaccinate down to 50 yo, that's missing alot of infected people who might want to try it.


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Rajahadmin
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Jan-30-13, 01:56 PM (CST)
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8. "I can check with some of the more academic folks.."
In response to message #6
 
I suspect that, while simplex and zoster are both in the herpes family, the antibodies are sufficiently different so that the shingles vaccine wouldn't be particularly effective against simplex.

"Do the Right Thing. It will gratify some people and astound the rest." - Paraphrased from Mark Twain


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Rajahadmin
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Jan-31-13, 07:03 AM (CST)
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9. "I did check with one of the more academic folks.."
In response to message #8
 
He thought it was very interesting and encouraging. We'll have more about it when he's got time to reply here.

"Do the Right Thing. It will gratify some people and astound the rest." - Paraphrased from Mark Twain


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eagledave
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Mar-10-13, 09:26 PM (CST)
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10. "RE: I did check with one of the more academic folks.."
In response to message #9
 
my doc got a waiver from the FDA (or someone in authority) so I could get the Shingles vaccine. I'm 49, so might not have been a big deal to make the exception.

Rajah, I'm thinking you're probably over 50 - why not get the vaccine? Or if you did awhile back, do you still have OBs?


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Rajahadmin
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Mar-11-13, 09:27 PM (CST)
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11. "I am over 60 and got the shingles vaccine last year.."
In response to message #10
 
Since I've used antivirals suppressively for a few years now, I've not had any OBs, even before the vaccine. Let us know how this works out for you. We're interested.

"Do the Right Thing. It will gratify some people and astound the rest." - Paraphrased from Mark Twain


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deb54
Member since Jun-21-10
439 posts
Mar-12-13, 12:29 PM (CST)
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12. "RE: How Many People Taking Acyclovir Got Shingles?"
In response to message #11
 
   Just wondering if you've ever done a poll as to how many people taking acyclovir or Valtrex suppressively have acquired a shingles infection? I know that when someone gets shingles they are usually prescribed Valtrex or acyclovir, so wonder if a study has been done for those of us using those meds all the time. I plan on getting the shingles vaccine when I'm 60 as that is when my insurance will pay for it and it was $220 this fall at Walgreen's. But I'm wondering if I even need the vaccine since I'm taking the acyclovir????


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eagledave
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Mar-28-13, 05:44 PM (CST)
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13. "RE: How Many People Taking Acyclovir Got Shingles?"
In response to message #12
 
LAST EDITED ON Mar-28-13 AT 05:48 PM (CST)
 
deb, looking at it the other way, if the vaccine works, then you wouldnt need to take the Meds. Are you sure you cant get insurance coverage after your 50th bday, maybe with a doc's recommendation?

I tried antivirals years ago, but they only prevented the surface eruption - I still had prodrome and pain for the duration of the OB. I was also concerned about organ damage (liver?), so it's just as well I stopped taking them.

It's only been about a month since I got the vaccine. I usually get OBs in the summer, so that will be the test for me. If I get an OB between now and next September, I will post about it, and if it was any different than usual.


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deb54
Member since Jun-21-10
439 posts
Mar-29-13, 07:58 AM (CST)
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14. "RE: How Many People Taking Acyclovir Got Shingles?"
In response to message #13
 
   Keep me posted eagledave on how you do this summer. I only take acyclovir to protect my partner as my OB's haven't been too bad. They really flared up after my husband died in 2006--had a year of monthly OB's and then when I started dating I wanted to do whatever I could to protect my partner. And I know my insurance won't pay until I'm 60 as I checked last year. Unfortunately the years are flying by and I only have 1 1/2 years to wait and acyclovir is cheap. No OB's at all since I'm on the acyclovir and I never had problems with pain, just prodromal tingling.


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Rajahadmin
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Mar-29-13, 05:23 PM (CST)
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15. "EagleDave, the herpes antivirals are very safe.."
In response to message #13
 
You don't need to worry about liver problems from using them. I know people who have used them for a couple decades without any such effect.

"Do the Right Thing. It will gratify some people and astound the rest." - Paraphrased from Mark Twain


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eagledave
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Mar-30-13, 10:22 AM (CST)
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16. "RE: EagleDave, the herpes antivirals are very safe.."
In response to message #15
 
that's probably reassuring news for people who take antivirals. I wasnt trying to discourage anyone, just explaining they were useless for me, and why a working vaccine would be much better. My first OB was in 1994 or 1995, and there was still concern about liver damage in longterm use, so the added "benefit" in not taking them was no nagging concern about that. And yes, I tried different antivirals later on.

My cat has chronic congestion which is sometimes caused by a virus; I recently suggested antivirals, but the Vet was hesitant from concerns of organ damage. We tried a low dosage (possibly too low, from what I've read) which didnt help. Anyway, it raised the old issue of organ damage in my mind.


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eagledave
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May-16-13, 07:13 AM (CST)
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17. "shingles vaccine didnt work for me"
In response to message #16
 
got an OB after 2.5 months, so the Shingles vaccine didnt work for me.


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Raven00144
Member since Sep-9-07
2523 posts
May-16-13, 08:22 AM (CST)
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18. "RE: shingles vaccine didnt work for me"
In response to message #17
 
   I was a long time user of acyclovir but only taking for OBs or to protect a partner, otherwise I would not take anything daily. When I needed a refill, the doctor's office switched me over to Valtrex. I have a partner that lives just over the border and we do not get together as often as we used to so I only take valtrex 5 days or sooner when I know we are going to meet up. My OBs are also not that often.

Last year a man that I work with (in his 40's) got a case of the shingles and my ex b/f (also in his 40's) that I visited in Florida was having a case while I was there. I contacted my insurance co. and they allowed me to get the shingles shot.

Since getting this shot, I have not had an OB. This could be because I do not get OBs that often anymore, I would take valtrex at the start of anything that did not feel right or because I had the shingles shot. At this stage of my life, my GHSVII is minor compared to what other things life is throwing at me.

My OBs can be managed with meds as well as protecting my partner. I just hope the shingles shot prevents a case of the shingles.

Raven00144


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Atifrazaa
Member since Dec-27-14
1 posts
Dec-27-14, 06:06 AM (CST)
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20. "RE: shingles vaccine didnt work for me"
In response to message #18
 
Hi there -
Anything is possible. Most info says that it wouldn't take that long to show up, but I work in an std clinic, and see this with some frequency.

If this is the only indication that you have that your hubby might have cheated, its not a good enough sign to prove it.

What steps are you taking next for treatment?

Good luck!!

Jess

atif


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eagledave
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Nov-20-13, 11:08 AM (CST)
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19. "RE: shingles vaccine didnt work for me"
In response to message #17
 
LAST EDITED ON Nov-20-13 AT 11:08 AM (CST)
 
the H Harmony site recommended getting a 2nd shot (a booster, I guess). In the report there were people who had a 2nd vaccination, which was distinguished from the booster shot 2 people requested - I dont know if they were using some kind of 2-shot vaccination, and booster was considered different. Anyway, perhaps I should have followed up with a 2nd shot when my insurance kicked in after my b-day.
I've had a couple more OBs, whereas study subjects didnt have any after the initial shot, so a booster might not help me either.


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