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Subject: "Do antivirals affect testing results?"     Previous Topic | Next Topic
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Maggieddd1
Member since Feb-9-13
6 posts
Mar-14-13, 09:22 PM (CST)
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"Do antivirals affect testing results?"
 
   About 28 years ago I was told I was positive for HIV I & II after a swap was taken during an outbreak on my lower back. Upon the advice of either of Lorraine or Grace I recently got retested. Surprisingly my HSV I came back negative at< .90. My lips do get very itchy and red & sometimes I feel like I have a paper cut at the corners Of my mouth which I thought was HSV I. I am on 500 mg of acyclovir/dy. Could the antivirals cause a false-negative result?


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Rajahadmin
Charter Member
15368 posts
Mar-16-13, 10:47 AM (CST)
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1. "That's a good question,,"
In response to message #0
 
I am assuming you meant HSV instead of HIV. 28 years ago, the testing was not as good as it is today in both sensitivity and the ability to differentiate between different types of the herpes virus. The lower back is a somewhat unusual place to get HSV1 unless you're a wrestler.

You mentioned that, 28 years ago, you also tested positive for HSV2. Did your recent testing check for that, too?

If you've been using valtrex suppressively for some time, it's somewha possible that it might affect the recent testing, but I'd like to hear from one of the medically trained folks on that. Why are you taking valtrex? Is it for your oral symptoms?

"Do the Right Thing. It will gratify some people and astound the rest." - Paraphrased from Mark Twain


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Maggieddd1
Member since Feb-9-13
6 posts
Apr-04-13, 08:51 PM (CST)
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2. "RE: That's a good question,,"
In response to message #1
 
   I'm so sorry I just noticed your reply.

Yes , I meant HSV not HIV. I got tested for both and came back positive for 2 and negative for 1. I'd only been on Valacyclovir for a few weeks. I take it because I thought I was going to be starting a relationship with someone and had been getting OBs on my lower back/ upper buttocks about 12+ times/yr. After initial OB in my mid 20s I had none until I hit mid 40s.

The Dr I spoke to on the phone who works for the STD testing site said that the tests in the 80s didn't differentiate. However, I remember getting what I thought was a cold sore as a kid so I think this must be a false negative as of heard the rate of false befatives is about 8%.However, the IgG for the type 2 came back at 5.0 so I guess the valacyclovir didn't affect that result. Thought it curious the Dr didn't speak of false negatives for type 1 even after I told her I was pretty sure I had it. Just wishful thinking on my part I guess


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Maggieddd1
Member since Feb-9-13
6 posts
Apr-04-13, 08:57 PM (CST)
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3. "RE: That's a good question,,"
In response to message #1
 
   I should add that the Dr. did not think the valacyclovir would have caused a false negative, however, the rep who took my number to set up the telephone consult said it would. A bit confused.

And no...... I'm not a wrestler


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Rajahadmin
Charter Member
15368 posts
Apr-09-13, 11:42 AM (CST)
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4. "Who do you trust?"
In response to message #3
 
A doctor or the sales rep on the phone? I think I'd go with the doctor.

"Do the Right Thing. It will gratify some people and astound the rest." - Paraphrased from Mark Twain


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